M. VIJAYAN

Research Interests

1. Structure, sugar specificity and multi-valency of lectins

 

Legume lectins

Peanut lectin

Winged bean lectins

b-Prism fold I lectins

 Jacalin from jackfruit seeds
Artocarpin from jackfruit seeds
Banana lectin

 


b-Prism fold II lectins                    b-Trefoil fold lectins

Garlic lectin                                                        Snake gourd lectin


 

2. Structural biology of mycobacterial proteins

 

Recombination and Repair

RecA from M. tuberculosis and M. smegmatis

 

Single-stranded DNA binding protein from  M. tuberculosis,     Uracil DNA glycosylase from                          M. leprae and M. smegmatis                                           M. tuberculosis

                

Protein Synthesis

Ribosome recycling factor from M.tuberculosis      Peptidyl-tRNA hydrolase from M.tuberculosis

CoA synthesis

Pantothenate kinase from M. tuberculosis

Stringent response

  Dps-1 from M. Smegmatis              Dps-2 from M. Smegmatis

 

 

3. Hydration, plasticity and action of proteins

Lysozyme

Ribonuclease A

Hemoglobin

b-Lactoglobulin and their low humidity variants

 

4. Supramolecular association and their implications to chemical evolution and origin of life

Crystalline complexes involving L-,D- and DL- amino acids and peptides, among themselves, and with carboxylic acids.
 


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