81. Redox regulation of the quorum sensing transcription factor AgrA by coenzyme A

Bakovic, J., Yu, B., Silva, D., Baczynska, M., Peak-Chew, S., Switzer, A., Burchell, L., Wigneshweraraj, S., Vandanashree, M., Gopal, B., Filonenko, V., Skehel, M., Gout, I.

Antioxidants 10:841. 2021


80. Novel insights into ATP stimulated cleavage of branched DNA and RNA substrates through structure-guided studies of the Holliday junction resolvase RuvX.

Thakur, M., Mohan, D., Singh, A. K., Agarwal, A., Gopal, B., Muniyappa, K.

J Mol Biol 433:167014. 2021


79. Draft genome sequence of the community associated Staphylococcus aureus sequence type 88strain LVP-7, isolated from an ocular infection.

Nadig, S., Murthy, S., Murali, V., Subramanya, H. S., Gopal, B., Vembar, S.

Resource Announcements 10: 00077-00021. 2021


78. Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe-4S cluster and regulates Fe-S cluster biogenesis for persistence

In mice.

Anand, K., Tripathi, A., Shukla, K., Malhotra, N., Jamithireddy, A. K., Jha, R. K., Chaudhury, S. N., Rajmani, R. S., Ramesh, A.,

Nagaraja, V., Gopal, B., Nagaraju, G., Seshasayee,, A. S. N., Singh, A.

Redox Biology 2021



77.Use of a molecular beacon based fluorescent method to assay uracyl DNA glycosylase (UNG) activity and inhibitor screening.

Mehta, A., Raj, P., Sundriyal, S., Gopal, B., Varshney, U.

BB Reports 26:100954. 2021


76. Structural and biochemical characteristics of two Staphylococcus epidermidis RNase J paralogues RNase J1 and RNase J2.

Raj, R., Nadig, S., Patel, T., Gopal, B.

J Biol Chem doi:10.1074/jbc.RA120.014876. 2020


75.Structural insights into the catalytic mechanism of Bacillus subtilis BacF.

Deshmukh, A., Gopal, B.

Acta Cryst F76:145-151. 2020


74. Evaluation of specificity determinants in Mycobacterium tuberculosis s /anti-s factor interactions.

Jamithireddy, A. K., Runthala, A., Gopal, B.

Biochem Biophys Res Comm 521:900-906. 2020


73. Destabiliation of Insulin hexamer in Water-Ethanol binary mixture.

Mukherjee S, Deshmukh AA, Mondal S, Gopal B, Bagchi B.

J Phys Chem B. 123:10365-10375. 2019


72. Selectivity among anti-s factors by Mycobacterium tuberculosis ClpX influences intracellular levels of Extracytoplasmic function

s factors .

Joshi, A. C., Kaur, P., Nair, R. K., Lele, D. S., Nandicoori, V. K., Gopal, B.

J. Bacteriol 25:pii e0048-18. 2019


71. The crystal structure of Mycobacterium tuberculosis high temperature requirement A protein reveals an autoregulatory mechanism.

Gupta, A. K., Behera, D., Gopal, B.

Acta Cryst F74:803-809. 2018


70. What gives an insulin hexamer its unique shape and stability? Role of ten confined water molecules.

Mukherjee, S., Mondal, S., Deshmukh, A. A., Gopal, B., Bagchi, B.

J. Phys. Chem B. 122:1631-1637. 2018


69. Characterization of the Staphylococcus epidermidis polynucleotide phosphorylase and its interactions with ribonucleases RNaseJ1 and RNaseJ2.

Raj, R., Mitra, S., Gopal, B.

Biochem Biophys Res Comm 495:2078-2084. 2018


68. The fused Snoal_2 domain of the Mycobacterium tuberculosis sigma factor σJ modulates promoter recognition.

Goutam, K., Gupta, A. K., Gopal, B.

Nucleic Acids Res 45:9760-9772. 2017


67. Determination of redox sensitivity in structurally similar biological redox sensors.

Jamithireddy, A. K., Samajdar, R. N., Gopal, B., Bhattacharyya, A. J.

J. Phys. Chem B 121:7005-7015. 2017


66. Design, synthesis and experimental validation of peptide ligand targeting Mycobacterium tuberculosis σ factors.

Vishwanath, S., Banerjee, S., Jamithireddy, A. K., Srinivasan, N., Gopal, B., Chatterjee, J.

Biochemistry 56:2209-2218. 2017


65.Probing the influence of non-covalent interaction networks identified by charge density analysis on the oxidoreductase BacC.

Kumar, P., Balaram, H., Guru Row, T. N., Gopal, B.

Protein Engg Des Select. 30:263-270.2017


64.The topology of the L-arginine exporter ArgO conforms to an Nin-Cout configuration in Escherichia coli: Requirement of the cytoplasmic N-terminal domain, functional helical interactions and an aspartate pair for ArgO function.

Pathania, A., Gupta, A. K., Dubey, S, Gopal, B., Sardesai, A. S.

J. Bacteriology 198: 3186-3199. 2016


63. A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains.

Shambat, S.M., Siemens, N., Monk, I. R., Disha Mohan B, Mukundan, S. Krishnan, K. C., Prabhakara, S., Snall, J., Kearns, A., Vandenesch, F., Svensson, M., Kotb, M., Gopal, B., Arakere, G., Norrby-Teglund, A.

Sci Reports 6: 31360-31372. 2016


62. Conformational features of the Staphylococcus aureus AgrA-promoter interactions rationalize quorum-sensing triggered gene expression.

Kalagiri, R., Fasim, A., Gopal, B.

Biochem Biophys Rep 6: 124-134. 2016


61.Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues

Shivastava, P., Navratna, V., Silla, Y., Dewangan, R. P., Pramanik, A., Chaudhary, S., Rayasam, G. V., Kumar, A., Ugarkar, B., Gopal, B., Ramachandran, S.

Sci Reports 6:30827-30844. 2016


60. Crystallographic studies of the extracytoplasmic function sigma factor SigJ from Mycobacterium tuberculosis

Goutam, K., Gupta, A. K., Gopal, B.

Acta Cryst. F71:946-950. 2015


59. Structural basis for the catalytic mechanism of homoserine dehydrogenase.

Navratna, V., Reddy, G. Gopal, B.

Acta Cryst. D71: 1216-1225. 2015


58. Influence of the AgrC-AgrA complex in the response time of Staphylococcus aureus quorum sensing.

Srivastava, S. K., Rajasree, K., Fasim, A., Arakere, G., Gopal, B.

J. Bacteriology 196: 2876-2888. 2014


57. Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA σ-anti-σ complex.

Shukla, J.K., Gupta, R., Thakur, K.G., Gokhale, R. S., Gopal, B.

Acta Cryst. D70: 1026-1036. 2014


56. Titania nanotube-modified screen printed carbon electrodes enhance the sensitivity in the electrochemical detection of proteins.

Mandal, S.S., Navratna, V., Sharma, P., Gopal, B., Bhattacharyya, A. J.

Bioelectrochemistry 98: 46-52. 2014


55. Bi-domain protein tyrosine Phosphatases reveal an evolutionary adaptation to optimize signal transduction.

Ahuja, L. G., Gopal, B.

Antioxidants & Redox Signalling 20: 2141-2159. 2014


54. Crystallization and preliminary X-Ray diffraction studies of Staphylococcus aureus homoserine dehydrogenase.

Navratna, V, Gopal, B.

Acta Cryst F69:1216-1219. 2013


53. Mycobacterium tuberculosis RsdA provides a conformational rationale for selective regulation of σ factor activity by proteolysis.

Jaiswal R K, Suryaprabha T, Manjeera G, Gopal B.

Nucleic Acids Res 41:3414-3423. 2013


52. The crystal structure of an amidohydrolase SACOL0085 from Methicillin Resistant Staphylococcus aureus COL.

Girish T S, Vivek B, Colaco M, Misquith S, Gopal B.

Acta Cryst F69:103-108. 2013


51. Structural insights into the role of Bacillus subtilis YwfH (BacG) in tetrahydrotyrosine synthesis.

Rajavel M, Perinbam K, Gopal B.

Acta Cryst D69:324-332. 2013


50. Analysis of conformational variation in macromolecular structural models.

Srivastava S K, Gayathri S, Manjasetty B A, Gopal B.

PLoS One. 2012;7(7):e39993. 2012


49. Inter-domain interactions influence the stability and catalytic activity of the bi-domain protein tyrosine phosphatase PTP99A.

Madan L L, Goutam K, Gopal B.

Biochem Biophys Acta. 2012 Aug;1824:983-90. 2012


48. Conformational basis for substrate recruitment in Protein Tyrosine Phosphatase 10D

Madan L L, Gopal B.

Biochemistry 50: 10114-10125. 2011


47. Modulation of catalytic activity in multi-domain protein tyrosine phosphatases

Madan L L, Veeranna S, Shameer K, Reddy C C S, Sowdhamini R, Gopal, B.

Plos One 6(9): e24766. 2011


46. Structure and nucleotide specificity of Staphylococcus aureus dihydrodipicolinate reductase (DapB).

Girish T S, Navratna V, Gopal B.

FEBS Letts. 585: 2561-2567. 2011


45. Conformational basis for substrate recognition and regulation of catalytic activity in Staphylococcus aureus

nucleoside di-phosphate kinase

Srivastava S K, Rajasree K, Gopal B

Biochem Biophys Acta (Proteins and Proteomics) 1814: 1349-1357. 2011


44. Structural Biology of Mycobacterium tuberculosis: The Indian Efforts

Arora A, Chandra N R, Das A, Gopal B, Mande S C, Prakash B, Ramachandran R, Sankaranarayanan R, Sekar K, Suguna K, Tyagi A K, Vijayan M.

Tuberculosis (Edinb) 91(5) : 456-468. 2011


43. PeptideMine A webserver for the design of peptides for protein peptide binding studies derived from protein-protein interactomes.

Shameer K , Madan L L, Veeranna S, Gopal B, Sowdhamini R .

BMC Bioinformatics 11 : 473. 2010


42. The crystal structure of Staphylococcus aureus metallopeptidase (Sapep) reveals large domain motions between the manganese bound and apo states.

Girish T S , Gopal B.

J. Biol. Chem 285, 29406-29415. 2010


41. Over-expression and purification strategies for recombinant multi-protein oligomers: A case study of Mycobacterium tuberculosis s/anti-s factor protein complexes

Thakur K G, Jaiswal R K, Shukla J K, Praveena T, Gopal B.

Prot. Exp. Purif. 74(2) : 223-230. 2010


40. Role of a PAS sensor domain in the Mycobacterium tuberculosis transcription regulator Rv1364c.

Jaiswal R K, Manjeera G, Gopal, B.

Biochem Biophys Res Comm 398, 342-349. 2010


39. Structural and biochemical basis for the redox sensitivity of Mycobacterium tuberculosis RslA

Thakur K G, Praveena T, Gopal B.

J. Mol. Biol.397, 1199-1208. 2010


38. Analysis of multiple crystal forms of Bacillus subtilis BacB suggests a role for a metal ion as a nucleant for crystallization.

Rajavel M, Gopal B.

Acta Cryst D. 66, 635-639. 2010


37. Inhibition of a protein tyrosine phosphatase using mesoporous oxides.

Kapoor S, Girish T S, Mandal S S, Gopal B, Bhattacharyya A J.

J. Phys. Chem B. 114: 3117-3121. 2010


36. X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate.

Chakrabarty K, Thakur G, Gopal B, Sarma S.

FEBS J. 277:697-712. 2010


35. Molecular Basis for the role of Staphylococcus aureus Penicillin Binding Protein 4 in antimicrobial resistance.

Navratna V, Nadig S, Sood V, Prasad K, Arakere G, Gopal B.

J. Bacteriology 192: 134-144. 2010


34. Mycobacterium tuberculosis Rv2704 is a member of YjgF/YER057c/UK114 family.

Thakur K G, Praveena T, Gopal B.

Proteins 78:773-778. 2010


33. Role of Bacillus subtilis BacB in the synthesis of the antibiotic bacilysin.

Rajavel M, Mitra A, Gopal B.

J. Biol. Chem 284:31882-31892. 2009


32. Structure-based phylogeny as a diagnostic for functional characterization of proteins with cupin fold

Agarwal G, Rajavel M, Gopal B, Srinivasan N.

PLoS One 4(5): e5736. 2009


31. Correlation between the sucrose synthase protein subfamilies, structure and expression in stress-derived Expressed Sequence Tag datasets.

Jayashree B, Pradeep R, Kumar A, Gopal B.

J. Proteomics Bioinformatics 1, 408-423. 2008


30. Refolding and simultaneous purification by three phase partitioning of recombinant proteins from inclusion bodies.

Raghava S, Barua B, Singh P K, Das M, Madan L L, Bhattacharyya S, Bajaj K, Gopal B, Varadarajan R, Gupta M N.

Protein Sci 17,:1987-1997. 2008


29. Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase.

Girish T S, Sharma E, Gopal B.

FEBS Letts 582,2923-2930. 2008


28. Conformational studies suggest that the double stranded b helix scaffold provides an optimal balance between protein stability and function.

Rajavel M, Kulkarni N N, Gopal B.

Prot. Pept. Letts 15, 244-249 2008


27. Addition of a polypeptide stretch at the N-terminus improves the expression, stability and solubility of recombinant protein tyrosine phosphatases from Drosophila melanogaster.

Madan L L, Gopal B

Prot. Exp. Purif.57, 234-243. 2008


26. Structural and biophysical studies on two promoter recognition domains of the extra-cytoplasmic function s factor sC from Mycobacterium tuberculosis.

Thakur K G, Joshi A M, Gopal B.

J. Biol. Chem 282, 4711-4718. 2008


25. The crystal structure of the catalytic domain of the chick retinal neurite inhibitor- Receptor Protein Tyrosine Phosphatase CRYP-2 / cPTPRO.

Girish T S, Gopal B.

Proteins 65,1011-1015. 2007


24. Crystallization and preliminary X-Ray diffraction studies on the bicupin YwfC from Bacillus subtilis

Rajavel M, Gopal B.

Acta Cryst F62, 1259-1262. 2006


23. Old fold in a new X-Ray diffraction dataset? Low-resolution molecular replacement using representative structural templates can provide phase information.

Rajavel M, Warrier T, Gopal B.

Proteins 64, 223-230 . 2006


22. Crystallization and preliminary X-Ray diffraction studies on the N- and C- terminal domains of the extra-cytoplasmic sigma factor SigC from Mycobacterium tuberculosis.

Thakur K G, Gopal B.

Acta Cryst F61, 779-781. 2005


21. Crystallization and Preliminary X-Ray diffraction studies on the catalytic domain of the of the chick neurite inhibitory factor CRYP-2.

Girish T S, Gopal B.

Acta Cryst F61, 381-383. 2005


20. The mechanism of upstream activation in the rrnB operon of Mycobacterium smegmatis is different from the Escherichia coli paradigm.

Arnvig K B, Gopal B, Papavinasasundaram K G, Cox R A, Colston M J.

Microbiology 151, 467-473. 2005


19. Crystal structure of a quercetin 2,3 dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site(s)

Gopal B, Madan L L, Betz S F, Kossiakoff A A.

Biochemistry 44, 193-201. 2005


18. A high affinity interaction between NusA and the rrn nut site in Mycobacterium tuberculosis.

Arnvig K B, Pennel S, Gopal B, Colston M J.

Proc. Natl. Acad. Sci (USA) 101, 8325-8330. 2004


17. Crystal Structure of the transcription elongation / antitermination factor NusA from Mycobacterium tuberculosis.

Gopal B, Haire L F, Gamblin S J, Dodson E J, Lane A N, Papavinasasundaram K G P, Colston M J, Dodson G.

J. Mol. Biol. 314, 1087-1095. 2001


16. Crystallization and preliminary X ray diffraction studies on the N-utilizing substance A (NusA) from Mycobacterium tuberculosis.

Gopal B, Papavinasasundaram K G P, Colston M J, Dodson G, Haire L F.

Acta Cryst D57, 1187-1188. 2001


15. Spectroscopic and thermodynamic characterization of the transcription antitermination factor NusE and its interaction with NusB from Mycobacterium tuberculosis.

Gopal B, Papavinasasundaram K G P, Colston M J, Dodson G, Major S, Lane A N.

Biochemistry 40,Jan 30 920-928. 2001


14. Tackling both the player and the ball: Lessons from crystallographic studies on the N-utilizing substance B (NusB) from Mycobacterium tuberculosis.

Haire L F, Gopal B.

J. Crystal Growth 232, 361-367. 2001


13. Variability of calcium binding to EF-hand motifs probed by Electrospray Ionization Mass Spectrometry.

Moorthy A K, Singh S K, Gopal B, Surolia A, Murthy M R N.

J. Am. Soc. Mass. Spectrom. 12, 1296-1301. 2001


12. Crystal structure of NusB from Mycobacterium tuberculosis.

Gopal B, Haire L F, Lane A N, Major S, Brannigan J A, Cox R A, Colston M J, Smerdon S J, Dodson G.

Nature Struct Biol 7, 475-478. 2000


11. Crystallization and preliminary X-ray diffraction studies on the N-utilizing substance B (NusB) from Mycobacterium tuberculosis.

Gopal B, Cox R A, Colston M J, Dodson G G, Smerdon S J, Haire L F.

Acta Cryst D56, 64-66. 2000


10. Structural and thermodynamic studies on protein stability.

Gopal B.

J. Ind Inst of Sci., 79, 551-553. 1999


9. Thermodynamics of target peptide recognition by Calmodulin and a Calmodulin analogue : Implications for the role of the Central Linker.

Moorthy A K, Gopal B, Satish P R, Bhattacharya S, Bhattacharya A, Murthy M R N, Surolia A.

FEBS Letts 461, 19-24. 1999


8. Temperature dependent cell transformation in a Calcium binding Protein from Entamoeba histolytica.

Moorthy A K, Gopal B, Gopimohan C, Murthy M R N.

Current Science 76, No. 7, 855-856. 1999


7. Disulfide Engineering at the Dimer Interface of Lactobacillus casei Thymidylate Synthase : Crystal Structure of the T155C /E188C /C244T mutant.

Velanker S S, Gokhale R S, Ray S S Gopal B, Parthasarathy S, Santi D V, Balaram P, Murthy M R N.

Protein Science 8, 930-933. 1999


6. Cavity Creating Mutation at the Dimer Interface in Plasmodium falciparum Triosephosphate isomerase : Restoring Protein Stability by Disulfide Crosslinking of Subunits.

Gopal B, Ray S S, Gokhale R S, Balaram H, Murthy M R N, Balaram P.

Biochemistry 38, 478-486. 1999


5. Effect of amino acid substitutions at the subunit interface on the stability and aggregation properties of a dimeric protein: role of Arg 178 and Arg 218 at the Dimer interface of thymidylate synthase.

Prasanna V, Gopal B, Murthy M R N, Santi D V, Balaram P.

Proteins 34: 356-368. 1999


4. Induction of a spectrascopically defined .transition by Guanidium hydrochloride on a recombinant calcium binding protein from Entamoeba histolytica.

Gopal B, Krishna Rao J V, Thomas C J, Bhattacharya A, Bhattacharya S, Murthy M R N, Surolia A.

FEBS Letts 441, 71-76. 1998


3. Crystals of a Thymidylate Synthase mutant offer insights into crystal packing and protein plasticity.

Gopal B, Prasanna V, Parthasarathy S, Santi D V, Balaram P, Murthy M R N.

Current Science 75, No. 3, 299-304. 1998


2. Crystallization and preliminary X-ray studies of a recombinant calcium binding protein from Entamoeba histolytica.

Gopal B, Suma R, Murthy M R N, Bhattacharya A , Bhattacharya S.

Acta Cryst.D54 1442-1445. 1998


1. Thermodynamics of metal ion binding and denaturation of a Calcium Binding Protein from Entamoeba histolytica.

Gopal B, Swaminathan C P, Bhattacharya S, Bhattacharya A, Murthy M R N, Surolia A.

Biochemistry 36, No. 36, 10910-10917. 1997